CYTOGENETIC ANALYSIS OF HUMAN URINARY BLADDER CANCER

Pathogenesis of human urinary bladder cancer

The pathogenesis of bladder cancer is being analyzed at several levels of biological organization, i.e., population groups, individual whole animal, tissue, cell, molecule, etc. Each of these levels provides opportunities for mechanistic studies. Yet the integration of these several levels into a cohesive fabric is incomplete. From a clinical point of view, the following seem of importance to h...

PHEOCHROMOCYTOMA OF THE URINARY BLADDER

One of the rarest tumors involving the urinary bladder is the pheochromocytoma. A case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. Twenty-four hour urine VMA was normal. The patient was never hypertensive except during surgical manipulation of the tumor. Biopsy of the bladder resulted in massive hemorrhage.

Urinary Bladder Cancer Treatment

Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity. Cancer is one o...

Urinary Bladder Cancer

Bladder cancer occurs after the fifth decade and more frequently in men than in women (sex ratio 2:1 to 3:1). It has been associated mainly with smoking, but also with occupational exposure to carcinogens from aniline dyes, paints, rubber, etc, and chronic irritation of the bladder mucosa due to bladder stones, or schistosomiasis. The main symptom is painless hematuria, which in the adult patie...

Causation of Urinary Bladder Cancer